Side effects of repeated, long-term use of corticosteroids include thinning of the skin, growth problems in children, stretch marks and infections. The risk of side effects from these medications depends on the strength of the drug, the amount used, the area it's applied to and how much actually enters the person's blood stream. Though milder corticosteroids are considered safe to use rather liberally, more potent, prescribed treatments will usually be used for a limited period of time, which a doctor will determine.
In more severe cases of eczema, where other treatments have failed, systemic steroids may be used. Instead of applying the steroidal medication to the top of the skin, it is injected into the body, or taken in pill form. These medications should only be used for a short time. Side effects can include skin damage, weakened bones, high blood sugar and/or blood pressure, infections, and cataracts. It is also dangerous to stop systemic corticosteroids abruptly, and patients must work closely with a doctor when changing doses or stopping treatment.
Antibiotics
Antibiotics can be prescribed by a doctor to treat secondary infections associated with eczema. Medications used to fight infection can come in ointment or pill form and are taken for a set period of time.
Antihistamines
Sedating antihistamines, which are best to take at bedtime, can help ease severe itching associated with eczema, and help restless sleepers and "scratchers" to sleep. The sedating antihistamines are more effective at relieving itching than the newer, non-sedating antihistamines, but these drugs cause drowsiness, and can affect an adult's ability to work and think, and childrens' ability to learn if taken during the day
